1. Despite the fact that, though.”
Kodomo no kuse ni, otona no hanashi ni kuchi o dashite wa ikemasen.
Children shouldn’t interrupt when grown-ups are talking. (Lit., Despite the fact [or considering the fact] you are a [mere] child, you are not to butt in on grown-up’s talk [the way you are doing].)
Ano hito wa nōryoku mo nai kuse ni, chii dake wa hoshigatte iru.
Despite the fact that he has no ability, all he wants is status.
2. Used at the end of a sentence to express censure or contempt.
Anata datte dekinai kuse ni …
As if you could do it yourself. (Lit., Despite the fact that even you couldn’t do it [you are trying to tell me how to].)
Jibun de mo wakaranai kuse ni …
As if you understood. (Lit., Despite the fact that even you don’t understand [you presume to give advice to others].)